Abstract Based on the inter-provincial panel data of China from 2011 to 2020, this paper uses the spatial Dobbin model to test the influence and mechanism of digital inclusive finance on the inter-provincial entrepreneurial level.The results show that digital inclusive finance can improve the level of regional entrepreneurship, and there is obvious spatial spillover effect. In terms of different dimensions, the coverage and digitization of digital inclusive finance have significantly improved the level of regional entrepreneurship, but the depth of use is not significant. In terms of different functions, the payment function and credit function of digital inclusive finance have significantly improved the level of regional entrepreneurship, and have a strong spatial spillover effect, while the insurance function is not significant. The mechanism test indicates that digital inclusive finance can promote regional entrepreneurship by improving the availability of regional financing and consumer demand, and this effect is more significant in economically underdeveloped areas and areas closer to Hangzhou, showing strong characteristics of inclusiveness.